Anti-inflammatory effect of Ficus benghalensis extract against acrylamide induced inflammation in Zebrafish larvae

Abstract

Ficus benghalensis, commonly known as banyan, is a tree that has been shown to have anti-inflammatory properties. The tree contains several bioactive compounds, including polyphenols, flavonoids, and carotenoids, which are believed to contribute to its anti-inflammatory effects. In addition, some studies have suggested that Ficus benghalensis may have a protective effect against inflammatory bowel disease (IBD), a chronic inflammatory disorder of the gastrointestinal tract. In animal models of IBD, treatment with banyan extract has been shown to reduce inflammation and improve the integrity of the intestinal barrier. In this study the antiinflammatory effect of FB extract was investigated in the acrylamide exposed zebrafish larvae. The FB extract reduced the neurotoxicity response in the zebrafish embryos by decreasing the oxidative stress condition. The antioxidant defense levels are upregulated and this condition showed that FB extract normalized condition. The AChE levels are maintained in the embryos exposure after the treatment. These results suggest that FB extract can be used as the protective agent.