POLYMER COATED DRUG ELUTED STENT FOR CARDIOVASCULAR DISEASES

Abstract

Cardiovascular disease (CVD) is one of the serious disease worldwide. Currently top ten cause of death in the world cause due to CVD. CVD includes many conditions like the Coronary Artery Disease (CAD), Ischemic Heart Disease (IHD), and aortic diseases [1]. To overcome this fatal disease many treatments have been introduced in the field of medicine, like angioplasty and the field of interventional cardiology extended its support by the introduction of stent. Stent is a small tube like arrangement that is deployed in the coronary artery after the plaque removal (block), to allow the free flow of blood through the artery. Initially, the stents were made up of metal source like stainless steel, Cobalt and termed as Bare Metal Stents (BMS). The disadvantageous of using these stents include reoccurrence of the plaque and neointimal hyperplasia. In order to overcome these draw backs, Drug Eluting Stents (DES) were introduced which deliver the drug at the site of plaque formation and reduce the multiplication of smooth muscle cell thereby reducing neointimal hyperplasia. Restenosis and thrombosis seems to be problem of stenting irrespective of the material used. Therefore, in the present investigation two different materials, Polypropylene (polymer) is introduce to overcome the stated problem.