A REVIEW ON BUCCAL DRUG DELIVERY SYSTEM

Abstract

Buccal drug delivery system is a promising drug delivery route that has gained significant attention in recent years. It offers several advantages over traditional drug delivery systems, including rapid onset of action, avoidance of first-pass metabolism, improved patient compliance, sustained drug release, reduced dosage requirements, and better safety profile. Buccal drug delivery system can bypass the gastrointestinal tract and first-pass metabolism, resulting in improved drug efficacy and reduced side effects. However, there are also several disadvantages, including variability of buccal mucosa, limited drug absorption, patient acceptability, difficulty in formulation, regulatory challenges, and cost. Careful consideration of these factors is necessary when determining the appropriate drug delivery system for a given medication. Overall, buccal drug delivery system offers a promising alternative for the delivery of various drugs, and its advantages make it an attractive option for improving drug delivery and patient outcomes.